Apr 26 2015

Exploring SBOs in Search of New Antibiotics

Published by at 11:12 am under Antibiotics,probiotic supplements

Scientists Explore Soil Borne Organisms in Search of New Antibiotics…
Soil is the origin for billions of forms of life-giving, yet still undiscovered bacteria.

 

“…Selman Waksman first used the word antibiotic as a noun in 1941 to describe any small molecule made by a microbe that antagonizes the growth of other microbes. From 1945–1955 the development of penicillin, (which is produced by a fungus) along with streptomycin, chloramphenicol, and tetracycline (which are produced by soil bacteria), ushered in the antibiotic age. Today, the evolution of antibiotic resistance by important human pathogens has rendered these original antibiotics and most of their successors largely ineffective, and if replacements are not found, the golden age of antibiotics will soon come to an end…” (1) 

Last week we talked about how the overuse of antibiotics, by humans and animals alike, has made antibiotics less and less effective and bacteria more and more resistant. Some antibiotics are now completely ineffective in treating what doctors have named “super infections”, which are bacterial infections that have mutated into a form that are no longer treatable with known antibiotics.  Unless new antibiotics are developed, people will be at risk of contracting a wide range of bacterial infections with dire consequences. (1) 

“…Antibiotic resistance keeps infectious-disease doctors up at night. For instance, there are some strains of tuberculosis that have developed resistance to all known antibiotics…” (2) 

As reported on NRP recently, there is hope in the area of antibiotic research…and it comes from the soil. Originally published in the journal Nature, researchers from Northeastern University in Boston discovered a natural compound from bacteria that may prove to be a potent new antibiotic.  This new compound “…is especially intriguing because it appears that it might not lose its germ killing potential…” (2) 

Researcher Kim Lewis and his team were experimenting with how to grow bacteria never grown before in the lab. According to Lewis,

“…The majority of bacteria (99%) on this planet are uncultured meaning they don’t grow on our petri dishes…” The researchers found that the only way they could culture certain bacteria was to return it to where it came from…the soil. (2) 

“…Most antibiotics are derived from natural products secreted by bacteria and fungi that live in the soil, including widely used drugs such as Terramycin, Vancomycin and Streptomycin…” (2) 

So, this team developed a contraption which holds bacteria-rich soil between two membranes. They then returned this vessel back into the soil from which the bacteria had been extracted. It was here that the bacteria began to grow and form colonies. Once the colonies had formed, they then transferred these colonies of bacteria back to the lab where they continued to grow in petri dishes. Here, the researchers were able to examine the natural compounds which had been secreted by this newly isolated soil bacteria and looked for possible new antibiotics. Once under their microscope, they discovered more than two dozen potential new antibiotics, including one which they named teixobactin. They were most intrigued with this one as it is deadly to several different kinds of disease causing bacteria, yet is not toxic to mice. (2)   

We find this part of the report to be so interesting as it demonstrates how naturally-occurring wonders of nature are just waiting to be discovered. These new antibiotic strains came from the soil and first had to be cultured within the soil. 

This is a perfect illustration of the nature of Body Biotics™ Bio-Identical SBO Probiotics Consortia™ which is cultured in its natural Prebiotics ancestral plant matter of humic and fulvic acids.  Body Biotics™ is derived from the soil, cultured within the soil matter and encapsulated in this nutrient-rich substance to provide a natural variety of gut and immune stimulating health benefits. *

These are benefits that “patented” Probiotics cannot offer, as you cannot “patent” nature. Therefore these Probiotics have been mutated (or synthesized) into something other than their natural state. You can “patent” a process, but you cannot “patent” nature.  So, if you find a Probiotic strain on a label that says it is “patented” or “patent pending”, you now know it is a Probiotic that is in some form other than nature.   

Lastly, from  this report:

‘…In the lab, the compound killed bacteria that cause serious staph infections, strep and tuberculosis.  But the best part came when they ran another set of crucial tests. The most intriguing thing about this compound is the apparent absence of resistance development…”2

“…It seems that disease-causing bacteria don’t become resistant to this antibiotic. And that’s because the antibiotic latches on to parts of the bacteria’s cell wall that can’t mutate. Mutations are how bacteria typically develop defenses against drugs…”  This is critical in the area of infectious disease research as scientists continue their search for resistance-free compounds.

Of course there are many hurdles to cross including costs, government regulations and the time involved in testing this new antibiotic on humans. But regardless of what the end result is with this particular antibiotic, this amazing team is on to something huge with their approach to studying and growing bacteria. (2)  And, we are certainly excited to see this kind of research into the true nature of Soil Borne Organisms.

Healthiest wishes,

Kelli

 

 

References:

  1. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731226/
  2. http://www.npr.org/blogs/health/2015/01/07/375616162/compound-from-soil-bacteria-may-help-fight-dangerous-germs

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